LIFELINES COVID-19 COHORT: INVESTIGATING COVID-19 INFECTION AND ITS HEALTH AND SOCIETAL IMPACTS IN A DUTCH POPULATION-BASED COHORT

Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort

Purpose The Lifelines COVID-19 cohort was set up to assess the psychological and societal impacts of the COVID-19 pandemic and investigate potential risk factors for COVID-19 within the Lifelines prospective population cohort.Participants Participants were recruited from the 140 000 eligible participants of Lifelines and the Lifelines NEXT birth co

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A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.

Repetitive elements (REs) comprise 40-60% of the mammalian genome and have been shown to epigenetically influence the expression of genes through the formation of fusion transcript (FTs).We previously showed that an intracisternal Vitamin K A particle forms an FT with the agouti gene in mice, causing obesity/type 2 diabetes.To determine the frequen

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